allopurinol side affects - Uric Acid Testing
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Uric Acid Testing

Definition

Uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine.

Purpose




Gout Symptoms The most common gout symptom is sudden, severe attacks of pain, tenderness, redness, warmth and swelling in some joints. It usually affects one joint at a time, especially the joint of the big toe, but can also affect the knee, ankle, foot, hand, wrist and elbow. Deposits of uric acid, called tophi, can appear as lumps under the skin around the joints and at the rim of the ear. In addition, uric acid crystals can also collect in the kidneys and cause kidney stones.


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 Curing Gout and Decreasing Your Chance of Heart Disease My career is centered around health! Therefore, my favorite part of the newspaper is the 'Health' Section. And while reading the daily paper, I noticed an article about gout! "Gout Increases Risk of Coronary Heart Disease". I instantly flipped the page and thought 'duh'. But, after thinking about my friend Greg, his family, our friendship, his life... I immediately flipped back and read the interesting article!

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People whose body's produce too much uric acid or are not able to effectively eliminate uric acid from the body are at very high risk of contracting gout. The most common site for uric acid accumulation is in the big toe, although other joints may also be affected by crystalline buildup of uric acid.

Key Terms

Fanconi's syndrome
A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
Gout
A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
Hyperuricemia
Excessively high levels of uric acid in the blood, often producing gout.
Purine
A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Uric acid
A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
Uricosuria
Increased levels of uric acid in the urine.
Wilson's disease
A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.

Further Reading

For Your Information

    Books

  • Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
  • Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
  • Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.

Bio



Precautions

Blood test

Patients scheduled for a blood test for uric acid should be checked for the following medications: loop diuretics (Diamox, Bumex, Edecrin, or Lasix); ethambutol (Myambutol); vincristine (Oncovin); pyrazinamide (Tebrazid); thiazide diuretics (Naturetin, Hydrex, Diuril, Esidrix, HydroDiuril, Aquatensen, Renese, Diurese); aspirin (low doses); acetaminophen (Tylenol); ascorbic acid (vitamin C preparations); levodopa (Larodopa); or phenacetin. These drugs can affect test results.

4. Avoid ice and heat. Unlike other types of pain, gout will often hurt more with exposure to heat or ice. 5. Drink water! Water will help the body flush excess uric acid thus decreasing your chance of gout. Drink 10-12 glasses of water per day.

Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout.

And the kicker! Men with gout were about 50% more likely to die from an acute heart attack than those men without gout! With millions of gout hospital visits each year, and over 500,000 coronary deaths per year... Can you understand the seriousness of gout?

Risks

Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded.

Preparation

The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.

4.) Avoid or limit Alcohol Consumption. 5.) Exercise on a daily basis! Try to get at least 15 minutes of activity per day. Herbal Formula for Gout & Joint Stiffness

Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome.

A European study reported a 16 year follow-up of over 9,000 men between 41 and 63 who entered the study with no evidence of coronary heart disease (CHD). After the study follow-up, most men continued to suffer with gout attacks but also were considered high risk for coronary heart disease. And as you might know, 1 out of every 5 deaths is associated with heart disease.

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5 Tips to Treat Your Gout 1. Find a pair of shoes that fit comfortably. Try finding a wider shoe that will offer more room for your toe.

The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.

Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts.

While sometimes consistent, pain caused by gout can come and go and arise suddenly without warning. Joints affected with gout are usually red, swollen, and especially tender. Gout can also be accompanied by mild fever.

To prevent future attacks, your doctor can prescribe a medicine to reduce uric acid buildup in your blood. Changing the way you eat can help you conduct your gout. Eat a healthy mix of foods so you get the nutrients you need. Limit foods like meat, fish, and beer. Drink plenty of water and other fluids.Life style changes such as limiting alcohol consumption, and limiting meals with meats and fish rich in purines can also be helpful in controlling gout. Weight loss may be very important this condition. You should also avoid certain animal proteins, such as: seafood; liver; kidney; heart; gizzard; sweetbreads; meat extracts; and gravy.

The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood.

Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood. This condition is called hyperuricemia. Supersaturated uric acid in the urine (uricosuria) can crystallize to form kidney stones that may block the tubes that lead from the kidneys to the bladder (the ureters).

Here is a list of some basic tips if you or a loved one is suffering from gout! 1.) Maintain Your Healthy Weight! 2.) Avoid Eating Meats (Purines)!

 
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One of the most common forms of arthritis is gout. Gout is characterized by joint inflammation accompanied by terrible pain and sometimes red, shiny skin covering the joint. An attack of gout appears suddenly, often overnight and most often affects the feet and ankles, with the most common area being the ball of the large toe. Gout can be cured by using natural products such as cherries, charcoal, diet, avoidance of alcohol and natural supplements like Arthritin.



Remember when you could sleep the whole night without a flare-up of gout? Do you remember what it was like to not have to wince with pain when you walk? Fortunately, gout is treatable and curable and these 6 suggestions will get you on the right path to treat your gout symptoms.

* Vitamin C with Bioflavinoids lowers serum uric acid levels.

How Gout Works Gout is characterized with excruciating pain in the joint at the base of the big toe. In fact, about three-quarters of gout sufferers suffer from this excruciating pain affecting the toe. The other areas of the body gout might affect include: the elbows, shoulders, hands, wrists, knees and feet. The gout sufferer's joints will become swollen and inflamed and a fever could also develop. Most often, gout symptoms can last for days (2-5 days). Simply stated, gout is caused by higher levels of uric acid in the blood. There are several reasons for this happening including: overweight, too little activity, too much alcohol, various medications, genetics, or even a health disease (hypertension, etc). Whatever the cause, you can cure your gout if you begin your treatment today!

Normal results

Blood test

Reference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly.

2. Keep your toe elevated when resting/sleeping. Allow gravity to reduce the inflammation on the gout inflicted joint. 3. Try to stay off the joint with gout. Any pressure exerted on the area will cause more pain and further damage to the area.

Gout is a painful and potentially disabling rheumatic disease and is one of the most common forms of arthritis. Gout accounts for approximately 5% of all cases of arthritis. Gout usually affects the first metatarsal phalangeal joint of the big toe (hallux) or the ankle joints. Gout most often affects the big toe but can also affect the ankle, knee, foot, hand, wrist and elbow. Approximately one million people in the United States suffer from attacks of gout. Gout is nine times more common in men than in women. It predominantly attacks males after puberty, with a peak age of 75. In women, gout attacks usually occur after menopause.

3.) Drink half your weight in water! In ounces that is! I weight 180 pounds so I would drink 90 ounces of water per day! Roughly, 11 cups of water per day!

Steve Warshaw - Certified Personal Trainer and Nutritionist With over 15 years expereience developing training and nutrition programs for top level executives from companies such as Microsoft, Boeing, and Symetra Corp, Steve has established himself as a health and wellness expert.

Diagnosis A definitive diagnosis of gout is from light microscopy of fluid aspirated from the joints (this test may be difficult to perform) to demonstrate intracellular monosodium urate crystals in synovial fluid polymorphonuclear leukocytes. The urate crystal is identified by strong negative birefringence under polarised microscopy and its needle-like morphology. A trained observer does better in distinguishing them from other crystals.

Beneficial Dietary Supplements: * Bromelain reduces inflammation in joints and improves digestion of proteins when taken with meals, * Vitamin B Complex aids digestion and supports the body's enzyme systems.

Alcohol and certain foods can trigger a gout attack. Events such as strokes, heart attacks or surgery may also cause gout. Gout is strongly associated with obesity, hypertension, hyperlipidemia and diabetes. Because of genetic factors, gout tends to run in some families. A variety of treatments can help you manage your gout. Traditionally treatment for acute gout has consisted of colchicine , which can be effective if given early in the attack. Gout often is treated with nonsteroidal anti-inflammatories (NSAIDs) such as naproxen (e.g., Anaprox, Naprosyn) and indomethacin (e.g., Indocin), usually for 3-7 days.

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Abnormal results

The critical value for the blood test is a level of uric acid higher than 12 milligrams per deciliter (about 3.4 ounces).

If you wish to learn more about Gout, Purines, or Uric Acid, check out Steve's s The Internet Guides. The Internet Guide: Uric Acid: http://gout.smartadssecrets.com/uric_acid

Gout can be a life and death ailment if left untreated! I immediately made a phone call to Greg to check up! Greg followed our simple Natural Gout Cure and cured his gout, lost over 20 pounds and his blood pressure was over 15 points lower! I jokingly told him that he will be our 'cure gout poster child'.

How did he do it? He was pro-active about curing gout and began living a healthy lifestyle! And you can too! A Natural Gout Cure- No mediations needed and NO side-effects

Urine test

Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours.

Description

The uric acid blood test is performed on a sample of the patient's blood, withdrawn from a vein into a vacuum tube. The procedure, which is called a venipuncture, takes about five minutes. The urine test requires the patient to collect all urine voided over a 24-hour period, with the exception of the very first specimen. The patient keeps the specimen container on ice or in the refrigerator during the collection period.

Urine test

Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified.

Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy.

The Gout Relief formula has herbs that help relieve joint pain and other herbs that help alkalize the body from excessive uric acid.

# Uric acid can accumulate in the blood and the tissues, ultimately crystallizing causing pain and joint stiffness. # Devil's Claw : Relieves pain and reduces inflammation. Acts as a diuretic, sedative, and digestive stimulant. # Good for gout cure, back pain, rheumatism, arterioscleroses, lumbago and gout symptoms. Read out Natural cures. Also check out for homeopathic remedies and online doctor


Myrtle Randolph

 
 
     
 
 





Learn More about Natural Gout Remedy

Did you know that there are numerous natural gout treatments that have been shown to be effective in many natural health studies? In fact, gout remedies have been around for thousands of years. For instance, gout was once known as the disease of kings because so many kings complained about the arthritis of their big toe. And if you think...


Gout is a painful inflammation of joints caused by accumulation of uric acid crystals. Uric acid is a normal chemical formed by the breakdown of purines, which in turn are an important component of the human body. Many foods contain purines especially seafood and meat. Unless a patient has a family history or is taking medication that can cause gout such as some diuretics it may be hard to...


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Recently, a gout and diet prevention study was published in by Dr. Hyon K. Choi and Gary Curhan in Arthritis Care & Research s June 2007 issue which examined the fact that, contrary to popular belief, coffee may not be as bad for gout sufferers as previously thought. Although gout patients have been told to stay away from coffee, there may be an ingredient in the beverage that can actually...


Gout is a common, painful form of arthritis. Gout is a condition in which the body has a problem in the handling of uric acid. Uric acid is a waste product that naturally occurs in the body. It is normally flushed from the body by the kidneys through urine. It causes swollen, red, hot and stiff joints. Gout occurs when uric acid builds up in your blood. Men are more likely to get gout than women...


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