structure of purine - Stop the Gout Attack
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Stop the Gout Attack

Do you know what part of the body indicates the start of a gout attack? If you said the big toe, you would be right. Unfortunately, modern medical research still hasn't discovered the reason why over 75% of gout attacks occur in the big toe is first. In addition, to the big toe other joints of the body may also signal a gout attack including the knee, ankle and elbow.


This study, based on the Zone diet, did have a positive effect on markers of insulin resistance: triglycerides, total cholesterol, LDL cholesterol ("bad" cholesterol) fell. HDL cholesterol ("good" cholesterol) did not fall. But my purpose in this article is mainly to describe its direct effect on uric acid levels and gout attacks.


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 structure of purineOne participant did not have a raised UA level before the start. It was about 5.9mg/dL. But we already know that gout can occur in people with normal uric acid levels, so this was not unusual.

Sweetened Drinks Americans are drinking more sugary soft drinks than ever, but is there a coincidental rise in occurrence of Gout as well?

The study can be found online if you search "Beneficial effects of weight loss associated with moderate calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: a pilot study." Copy and paste this into a search engine search box and hit enter.

So a fall of 1.7 mg/dL, given these numbers, is quite significant, although you should note that many gout sufferers have UA levels much higher than 7.2 mg/dL, and some gout sufferers do not have excess uric acid.

After four months on this diet the effects on uric acid levels and gout attacks were quite impressive. Weight loss and uric acid levels Weight loss over the period was almost 17lbs (7.7kg) i.e. at a rate of about 1lb a week. All but one of the patients lost weight. The median uric acid (UA) fall was 1.7mg/dL.Another very interesting finding was that a more elevated blood uric acid level at the start of the study, meant a large fall of blood uric acid by the end of it. Uric acid levels normalised in 7 of 12 patients who had raised levels of uric acid (UA) before the study.

Learning what it takes to successfully cure or treat Gout is as important as knowing the root causes behind it. First you need to understand what causes Gout so that you can avoid Gout as well as treat Gout.

Look closer at our every day consumption of liquids and their up close and personal relationship with Gout. Prevention of Gout is not that difficult. What you need is proper knowledge to treat Gout.

How to Fight Gout? Fighting gout is not as hard as it appears to be when you really look at the pain and swelling caused by gout. The best way to fight gout is to make changes to your behaviour and eating habits like taking a walk after dinner to loss some of the calories you had at dinner. In addition, you also want to add specific foods that have been proven to help dissolve the jagged crystals in the joints.

Were the study patients taking long term medications, such as Allopurinol, for their gout? They were not. They were only taking medications for gout attacks. The study report did not say how much water they drank. Most gout sufferers know that drinking lots of water helps to remove uric acid. In gout treatment there are always caveats. The study was small. Only 13 male gout sufferers. The study lasted just four months, although there were follow-up results after one year (median). The researchers noted a connection between weight loss and a fall in uric acid levels in another study and expected the nutrient proportions (40:30:30) contributed to the uric acid fall. They thought that the dietary measures caused the desired improvement in insulin sensitivity.

Beer carries the most risk, not only contains alcohol, which can cause dehydration, but it contains Purine as well. As discussed earlier, the higher amounts of Purine roaming in the body, the more Uric Acid will answer the call. And it is the Uric Acid crystals that cause the excruciating pain associated with Gout!

This is the second article of a series about this diet. Please see Natural Gout Treatment - The Rules Of A Gout Diet That Had A Lot Of Success, for the first article.

??? Cherry juice concentrate is a highly concentrate way to get the pain relieving property of the tart cherry. It takes approximately 100 cherries to make just one ounce of tart cherry juice. A reliable source for tart cherry juice concentrate is Traverse Bay Farms http://www.traversebayfarms.com ??? Tart cherry capsules are made with tart cherry powder. The tart cherry powder is made using the freeze-dried process. The freeze dried process uses low heat and low temperature, thus maintaining 100% of the phytochemicals of the tart cherry. A good source of tart cherry capsules is Fruit Advantage http://www.fruitadvantage.com ??? Dried cherries not only taste great but this is a very versatile food to enjoy as a snack or an addition to almost any recipe. A good source for dried cherries is the website called Dried Tart Cherries. http://www.driedtartcherries.com ??? Although, fresh tart cherries are the best way to go, they are only available for a few short weeks during the summer so to ensure you get the benefits tart cherries you may consider the cherry juice, cherry capsules or dried cherries. A good source for fresh tart cherries is Jones Brothers Farms.

What is the Cause of these Painful Crystals? Here is a brief list of some of the top causes of the causes of these painful crystals, aka gout:

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In the study report, uric acid levels were expressed as mmol/l. In this article I have converted these mmol/l numbers to mg/dL, which is a more frequently used measurement.

We expect that approximately two-thirds of the Uric Acid to be removed from the body through the kidneys and urinary system. Gout occurs when the Uric Acid is not metabolized properly enough to send it into the urinary system, so the blood levels reach higher proportions. Once there, the crystals may find a cozy joint (usually at the site of a big toe) to gather and collect and proceed to wreak havoc by means of intense, sudden pain and off-the-charts inflammation.

Since our bodies rely heavily on the urinary system to rid us of excess Uric Acid, it is easy to understand why good hydration and fluid balance is so important. The balance of fluids in our systems plays an integral role in Gout prevention, cure and Gout treatment.

The benefit of the tart cherry is this little fruit is available is a variety of options including tart cherry juice, tart cherry capsules, dried cherries and the fresh fruit. Here is an brief overview of the different ways to fight gout with tart cherries:

But it goes further. Sugary fruits and juices such as apples and oranges appear to carry an increased risk of Gout as well. For the person trying to avoid Gout flare-ups, the ill effects of sweetened soft drinks proved to be worse than hard liquor and almost as negative as beer. Fructose appears to be the culprit, having been found to raise Uric Acid levels.

To treat and prevent Gout effectively, switch to water, low sugar juices or diet sodas and drink plenty of them.

Alcohol News flash: Drinking alcohol increases the risk for Gout! There is a proven and direct association between alcohol consumption and the presence of Gout. Therefore, if you are an avid drinker, there's no way you can avoid Gout. The risk is greatest for beer drinkers followed by those indulging in liquor, but wine (in moderation) does not seem to have much of an effect on the incidence of Gout.

The home remedy can include NSAID's but you may want to get a diagnosis first since other conditions can cause joint swelling including other forms of arthritis such as osteoarthritis and rheumatoid arthritis. Sometimes a joint infection can also look like gout especially if it is hot and red and swollen. If it is quite clear that it is gout, especially if it has affected a joint before, local ice and heat may be applied if comfortable. Taking an NSAID will help as long as the side effects are kept in mind which include stomach ulcer formation and at times high blood pressure. Some examples of NSAIDs are ibuprofen, naproxen and indomethacin.

 
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In addition to preventing Gout's acute attacks, the effects of good hydration helps keep joints lubricated, flushes Uric Acid out of the body and away from the poor great toe and other inflicted joints and prevents or helps kidney stones pass through if present. The kidneys cannot function optimally in a dehydrated state, nor does any system in the body.

Coffee Studies have been conducted that connect the drinking of coffee - and the more of it the better - with marked prevention of Gout in significant numbers of participants. Experts conclude that there is a correlation between elevated insulin levels and the presence of higher Uric Acid levels in the bloodstream. The researchers believe that drinking coffee lowers the level of insulin, and with it decreases the Uric Acid levels. Drink another cup of java and help yourself avoid Gout!

1. If you have a family history of gout, you may also suffer from gout. 2. Being overweight also contributes to gout. 3. Drinking excess alcohol or people drinking large amounts of alcohol on a continued basis can contribute to gout. 4. People how had an organ transplant are more likely to have gout than those who have not an organ transplant. 5. Men are more likely to get gout than women, however more women are getting gout. 6. The consumption of high purines food including seafood, alcohol and meats like kidney's and liver.

Read on... Water The most abundant home remedy to prevent Gout on the planet is at our fingertips. Water! There is no cheaper alternative to treat Gout. An individual seeking to prevent Gout or curing Gout it would be wise to drink as much as 96 ounces of water per day to maintain hydration and dilution of Uric Acid crystals in the bloodstream.

The results were sufficiently impressive to give hope and encouragement to any gout sufferer who tries this diet as accurately as possible. The study was conducted in 1999. Unfortunately it has not been followed up by a much larger one designed on the same lines. If conducted, such a study would expand our knowledge of natural gout treatment, perhaps considerably. A natural gout cure is what most gout sufferers want.

Note especially that the mean uric acid (UA) fall was 1.7mg/dL. In a couple of cases it fell by 2.2 mg/dL and by 2.5mg/dL respectively. Hyperuricemia, (excess uric acid), which may lead to gout, is reckoned to exist if the UA levels exceed 7.2 mg/dL (men), and 6.0 mg/dL (women). The usual UA target in gout treatment is 6.0 mg/dL (somewhat less in women) because at this level the MSU crystals, formed mainly from uric acid may dissolve. (It is the immune system's response to these crystals, which it regards as foreign bodies, which causes the pain and inflammation of gout).

And gout attacks? Results overall were expressed as a median. Before the study, participants had at least two attacks in the preceding four months. Median monthly attacks before the study were 2.1. After it, attacks fell to 0.6. The fall in the number of gout attacks occurred in all except one patient. The exception participant had shorter and less severe attacks. Eight of the 13 did not have a gout attack during the four month study period, although as mentioned, they had all had at least two in the previous four months and, as noted above, the median was 2.1 a month, or one attack a fortnight, (every two weeks).

The cycle of Gout begins with the presence of a substance called Purine, which is formed during the normal decomposition of protein molecules in our cells. A by-product of Purine is a crystalline substance called Uric Acid.

Gout is a painful and sudden illness that can affect joints. It is caused by the accumulation of excess uric acid, which is normally removed through the urine. The crystals of uric acid can then accumulate in joints and cause inflammation and pain. Often patients are not able to get to their healthcare provider right away. If it is a first attack the symptoms can be alarming. Fortunately, it is rarely life threatening and often resolves in a few days even without treatment. However everyone who gets an attack should see their healthcare provider since there are many excellent treatments available. But what can one do while at home?

During one 12-year study, it was concluded that the risk for developing Gout was significantly increased in participants that drank at least six servings of sweetened carbonated soft drinks per week (these were non-diet sodas).

Decreasing the intake of alcohol is also helpful since alcohol affects the elimination of uric acid. Although the effect of foods that cause gout is only small it must not be forgotten. Meat and seafood are common causes of gout if taken in excess.

One food you should add to your diet is the tart cherry. This ruby red fruit has been proven to help dissolve the crystals in the joints. Based upon medical university research the antioxidants naturally found in the tart cherry, including Anthocyanins, flavonoids and over 17 other natural compounds actually help to reduce inflammation in the joints.

Elevated levels of Purine present in the body at any given time, whether due to genetics or a high protein diet, may give rise to elevated amounts of Uric Acid in the blood stream.

Gout is actually a form of arthritis. Gout pain is the result of the build up of uric acid in the body. Uric acid is a result of crystal-like formations that travel in the blood stream. These jagged crystals are the cause of the redness, swelling and pain that gout is infamously known for.

Got beer? In order to prevent Gout, treat Gout or cure Gout, you already know the answer!

Betty Roberts is the author of Gout-Info.com, a website dedicated to Gout sufferers.

Tip: Counter the ill effects of dehydrating liquids you consume, by drinking more water or decaffeinated teas and low sugar juices. Water is the key to good health. It is the cheapest medicine known to man. And it can take a commanding role to successfully treat Gout.

Recent research has shown that vitamin C lowers uric acid level but whether this means something in patients with gout is not clear. Avoiding medication that cause gout such as diuretics or "water pills" or adjusting doses after discussing with the healthcare provider can also help.

AFTER ONE YEAR About a year later, five of nine patients had no more gout attacks and three had just one attack. So there was a further decrease in attack frequency overall. One patient gained weight after the end of the study. He must have given up on the diet. He suffered three attacks over three months. His blood uric acid levels rose with his weight.

NB. The contents of this article contain medical information not medical advice. Please always discuss remedies with your doctor or other health care professional before implementing any treatment.

You can prevent Gout. Follow the steps and tips listed here. To avoid Gout or hasten the process of curing Gout avoid Purine rich foods and beverages such as organ meats, poultry, seafood and products containing yeast.

John Mepham has spent much time researching gout. His best tip for curing gout naturally? Get to your ideal weight whatever the sacrifices may be. Learn more about this study and about natural gout treatment at www.gout-smashers-guide.com It's an e-book with a emphasis on natural gout treatment. The Zone diet, and other books by Barry Sears, are available at Official site of The Zone Diet The books can be found by clicking on the products tab on the home page.


Myrtle Randolph

 
 
     
 
 





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