pharmacology of colchicine - Cherries as an Effective Natural Remedy for Gout
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Cherries as an Effective Natural Remedy for Gout

Gout is a type of arthritis caused by the excessive accumulation of uric acid inside the organism. In large amounts, uric acid forms crystals which deposit in various regions of the body, causing inflammation, pain and swelling of the joints. Uric acid is a waste product that results from purine metabolism. Although most cases of gout are hereditary, occurring due to genetically acquired renal dysfunctions which determine an inappropriate elimination of uric acid, gout is more likely to occur in people who consume large amounts of purine-rich foods. Thus, an appropriate diet and lifestyle improvements can successfully alleviate the symptoms of gout and can actually reverse the undesirable effects of the disease.


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"week ago i couldnt walk and was in terible pain. i though my big toe was broken i would need a surgery, but doctor said it was gout. After taking some pain killer and goutezol for 2 days i can walk again. thank you" Peter from Chicago
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About the author:
Jeffrey A. Oster, DPM, C.Ped is a board certified foot and ankle
surgeon. Dr. Oster is also board certified in pedorthics. Dr.
Oster is medical director of href=http://www.myfootshop.comMyfootshop.com and is
in active practice in Granville, Ohio.

4. Vitamins! Studies have all indicated that sufferers usually have a vitamin deficiency. Vitamins A, B5 and E are critical to your diet. These 3 vitamins have been shown to block the formation and advancement of gout symptoms.

Although there are many factors that can contribute to a build up of uric acid within your system, alcohol consumption appears to be a leading factor in gout development. However, this doesn't mean that people who drink alcohol modestly on a regular basis will develop gout. Furthermore, research has discovered that different types of alcoholic beverages have different impacts on uric acid levels.

What's the actual physical change that takes place in the joint with turf toe? As an easy analogy, consider the changes that takes place when an apple falls from a height and is damaged. The skin of the apple appears intact but the underlying pulp is damaged. In the case of turf toe (hallux limitus), think of the skin of the apple as the cartilage of the joint and the damaged pulp of the apple is the subchondral bone. Mild cases of turf toe (hallux limitus), result in little damage to the subchondral bone and will merely exhibit signs of inflammatory change within the joint. Most authors would refer to these cases as stage one turf toe (hallux limitus). More severe cases result in damage to the joint surface, the subchondral bone or both. These are the stage two and three cases of turf toe (hallux limitus) that show visible change on x-ray. As the subchondral bone becomes increasingly damaged, it will create an uneven supporting surface for the cartilage. An increase in activity results in uneven loading of the joint due to the compression injury of the subchondral bone.

But before we go any further, we need to understand that the terms turf toe and hallux limitus aren't really synonymous. The fundamental difference between the two terms is the patient population that they affect. Turf toe is a term used in athletic circles referring to any injury of the great toe joint. Consequently, discussions about turf toe will focus on the first two causes of hallux limitus mentioned above; functional hallux limitus and direct physical injury. On the other hand, when we discuss hallux limitus, we're actually referring to a broader, 'non-athletic' patient population and need to include all three causes of hallux limitus.

What has been discovered is alcohol may not only affect the production of uric acid, but also its removal from the body. It appears that when alcohol is changed into lactic acid, it decreases the quantity of uric acid that the kidneys are able to remove from the body. The reason is because uric acid has to compete with the lactic acid in order to be removed by the kidneys.

References: Lombardi, C.M., Silhanek, A.D., Connolly, F.G., Dennis, L.N., Keslonsky, A.J. First Metatarsophalangeal Arthrodesis for Treatment of Hallux Rigidus: A Retrospective Study. J. Foot Surg. 40:3, 137-143, 2001

5 Simple Gout Remedies 1. Flush your body! Most people do not know that they are dehydrated. It is said that 80% of Americans are dehydrated. And research shows that most gout sufferers are in that category. You should be drinking at least 12 tall glasses of water a day if you suffer from this disease. Water flushes the body of uric acid, cholesterol, toxins, plaque, chemicals and many impurities.

Millions of people search for gout remedies each day hoping to find a way to get rid of the most painful type of arthritis. And most people who succeed in treating gout naturally are able to do so with simple home remedies that involve lifestyle changes.


Differential Diagnosis: The differential diagnosis of turf toe includes; Arthitis Fracture Gout Joint infection Joint or bone tumor Synovitis

Both sweet cherries (dark cherries) and sour cherries (ruby-red cherries) have proved to be very benefic for gout sufferers. Sweet cherries contain few calories and are rich in natural fibers. Sweet cherries contain melatonin, a chemical that has sedative and analgesic effects. Thus, the intake of sweet cherries can also ease recurrent gout pain. In addition, this type of cherries contains a powerful natural antioxidant that acts similarly to vitamin C. Sweet cherries can also lower the levels of inflammatory substances such as nitric oxide and C-reactive protein, chemicals that are related to gout, diabetes and heart disease.

What's so risky about beer? Some researchers believe that beer has a non-alcoholic ingredient that makes the increase of gout even higher than other alcoholic beverages. Beer is apparently the only alcoholic beverage to include purines, and an excessive amount of purines in the system can lead to higher production of uric acid. Conversely, other researchers do not believe it is the purines in the drink that increase the risk of gout. These researchers don't believe that having too many purines in the diet increase the risk of gout. Their reasoning is based on a study that was conducted on vegetarians from Taiwan who indulged in a diet that was high in purines. The study revealed that theses individuals actually had a lower risk of developing gout.

Unger, K., Rahimi, F., Bareither, D., Muehleman, C. The Relationship Between Articular Cartilage Degeneration and Bone Changes of the First Metatarsophalangeal Joint. J. Foot Surg. 39:1 24-33, 2000

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Treatment of turf toe varies with the type of healthcare provider and includes the use of rest, shoe modifications, orthotics, steroid injections and surgery. The success of non-surgical care will vary with the degree of injury, the rate at which the injury is healing and how much osteoarthritis has occurred. We see varying degrees of success with orthotics that promote plantarflexion of the first ray, effectively treating metatarsus primus elevatus and peroneus longus dysfunction. Simple arch supports can make a significant difference in the symptoms of turf toe. Should our patient not respond to conservative care in a reasonable time period, we are not reluctant to suggest surgical revision to address the problem whether it be revisions of the joint defect, shortening of a long first metatarsal or structural revision of metatarsus primus elevatus. As mentioned before, the clinical appearance of dorsal lipping or visible radiographic changes are suggestive of moderately advanced osteoarthritis, a condition that is only repaired by joint revision or replacement.

Sour cherries seem to reduce gout pain and inflammation and they also contain natural antioxidants that can decongest the arteries clogged with uric acid crystals. Sour cherries are rich in vitamin A, they contain very few calories and they can be safely introduced in any gout diet. Recent studies have revealed that by consuming around 100 grams of cherries each day, gout sufferers can experience a rapid amelioration of their symptoms. Although it is best to consume them raw, cherries can also be introduced in various recipes. Thanks to their remarkable qualities, cherries should be included in any diet.

For hundreds of years, medical researchers have suspected that gout is linked to specific lifestyles such as diets high in red meat, salt and alcohol, combined with little to no exercise. This type of lifestyle, which many people in Western countries tend to adopt as they become older and closer to middle age, is very much like the lifestyle that was once led by English kings. In fact, gout is often called "the disease of kings".

Functional hallux limitus - biomechanical function that results in metatarsus primus elevatus and subsequent repetitive jamming of the first MPJ. Direct physical injury - injury to the articular cartilage or subchondral bone. These injuries may be due impaction injuries or hyperextension/flexion of the first MPJ.

Anybody who has ever been diagnosed with gout knows that it can be extremely painful. Most people resort to some kind of painkiller which treats the pain but does NOT treat the uric crystals that cause gout. And people who use painkillers tend to damage the joint completely and allow gout to ruin their kidneys and lives.


Anatomy: The great toe joint, or first metatarsal joint consists of two bones. The proximal bone is the first metatarsal and the distal is called the proximal phalanx or hallux. These two bone move against each other in an up and down motion through what we refer to as the sagital plane. Biomechanics: The motion of the great toe joint is dependant upon the plantarflexion of the first metatasal. If the first metatarsal is limitied in its' ability to plantarflex, the joint will jam resulting in funtional hallux limitus, which as we know is one of the causes of turf toe.

 
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Regardless of the alcohol beverage you enjoy, you can dramatically reduce your risk of developing gout by drinking modestly (IE a glass of wine or beer per day). Overindulging in alcohol on occasion isn't going to have a dramatic effect on your chances of getting gout, but regular overindulgence may eventually lead to a serious pain in the big toe.

Ronconi, P., Monachino, P., Baleanu, P.M.,Favilli, G. Distal Oblique Osteotomy of the First Metatarsal for the Correction of Hallux Limitus and Rigidus Deformity. J. Foot Surg. 39:3, 154-160, 2000

So, if it's not the purines in beer then what is it? Some experts have a hunch that excessive beer drinkers have a higher risk in contracting gout due to their lifestyle. For instance, a person who drinks wine usually has their alcoholic beverage with a meal, or with healthy snacks such as fruits, vegetables, crackers and cheese. A beer drinker, on the other hand, will often indulge in eating salty and fatty snacks such as peanuts and chips, while they sit and watch TV on the couch hour after hour. Thus, enthusiastic beer drinkers are likely to have a more sedentary lifestyle.

But before you run to the doctor and get some painkillers, you might want to try some simple gout remedies that flush uric acid (the cause of gout) and drastically reduce gout attacks.

When treating turf toe be sure to recognize the fact that there is no nerve innervation in articular cartilage. Pain associated with stage one turf toe (hallux limitus) is either synovial pain or bone pain. If we recognize that painful stage one turf toe (hallux limitus) may be due to bone pain, we then realize that turf toe should be treated aggressively to insure the long term viability of the joint.


Symptoms: Turf toe that is the result of functional hallux limitus is going to be insidious in onset. Functional hallux limitus will usually be seen in younger athletes as they attempt to increase their activity. It may not occur during the first athletic season, or the second, but when it does begin to cause pain, the onset will be more frequent and more severe, varying with activity. This profile of onset is simply due to the fact that the athlete is recreating the injury with every step. Turf toe caused by a direct injury to the joint may or may not be obvious. Athletes may not remember an incident of pain since they're often distracted by the event or game in which they're involved. The onset of direct injury to the joint may be abrupt, but also may be insidious becoming increasingly more painful as the season progresses. The joint pain will subside with rest only to recur with increased activity. It's not unusual to see symptoms of turf toe resolve in the off season only to recur with renewed exercise.

Think of turf toe (hallux limitus) as an isolated case of osteoarthritis limited to the first MPJ. Whether the injury is acute or due to repetitive loading, the result is a load that is applied to the subchondral bone that is greater than what the bone can tolerate. As the injury progresses, a series of micro fractures will develop in the subchondral bone. The typical soft spongy character of the metaphyseal bone changes to become brittle and hard. The result is that the articular cartilage looses its' underlying support and becomes susceptible to damage. Juxtachondral eburnation, osteophytes, lipping, spurring; call them what you like, but what you see on your x-ray is the slow progressive destruction of the joint.

3. Purines! As stated earlier, purines are a cause of gout. You should moderate your intake of purines immediately. If the body does not have purines to convert to uric acid, you will have fewer and fewer attacks. Here is a list of the high purine foods: red meat products, gravies, shellfish, fish, and dried beans. For a complete food guide, please check out our Gout Remedy Report.

Currently you body is processing too many purines which turn into uric acid. If the blood stream contains too much uric acid, it will form into uric crystals which reside between joints (in most cases the big toe). If gout is not treated by flushing the uric acid, kidney damage will result.

Why You Lifestyle is Important Think about a time in your life when you were the healthiest. I can venture to guess that you didn't have gout during that period. And as you get older you might think that gout is a natural process of getting older. You are wrong! But the good news is that you can naturally treat gout with some simple do's and don'ts.

5. Move! Though it might hurt at first you should try to exercise between attacks. Exercise has hundreds of benefits but it also flushes impurities out of your body and keeps your body running efficient. Start with a short 10 minute walk and increase each week.

Today, researchers that have conducted studies on men in relation to alcohol consumption and its link to gout, have found that men who drank excessive amounts of certain forms of alcohol - especially beer - greatly increased their risk for developing gout.

Fortunately, gout is a warning sign to tell you that you need to watch what you eat. Your diet could be one thing that could help or hurt your gout symptoms.

Turf toe gets no respect. Let's take a closer look at the causes of turf toe and see how to treat it more effectively. Turf toe is actually a form of hallux limitus. Hallux limitus is classically described as pain and progressive decrease in the range of motion of the first metatarsal phalangeal joint (MPJ). The onset of hallux limitus is due to the following:

Is the onset of turf toe always the same? Turf toe that is the result of functional hallux limitus is going to be insidious in onset. Functional hallux limitus will usually be seen in younger athletes as they attempt to increase their activity. It may not occur during the first athletic season, or the second, but when it does begin to cause pain, the onset will be more frequent and more severe, varying with activity. This profile of onset is simply due to the fact that the athlete is recreating the injury with every step.

There are many natural products that can reduce serum uric acid concentration. Gout sufferers are advised to eat plenty of fiber-rich vegetables (preferably raw) and fresh fruits, as they contain low levels of purines and they are also a great source of vital nutrients. Among all fruits, cherries seem to be the best natural remedy for gout. Apart from being irresistibly delicious, cherries have anti-inflammatory, sedative and analgesic properties, and they can considerably ameliorate the clinical manifestations of gout. A frequent intake of cherries can considerably reduce the duration and the intensity of gout attacks, by normalizing uric acid levels inside the body. Recent studies have revealed that by including cherries in their diet, gout sufferers are able to eliminate more uric acid through urine. Thus, cherries act as a purgative agent, aiding the process of excretion.

Turf toe caused by a direct injury to the joint may or may not be obvious. Athletes may not remember an incident of pain since they're often distracted by the event or game in which they're involved. The onset of direct injury to the joint may be abrupt, but also may be insidious becoming increasingly more painful as the season progresses. The joint pain will subside with rest only to recur with increased activity. It's not unusual to see symptoms of turf toe resolve in the off season only to recur with renewed exercise.

2. Fiber! You should also eat fiber which causes your body to flush and detoxify itself. Eat at least 7-8 servings of fruits and vegetables a day. Fruits and veggies are high in water soluble fiber which will also flush your attacks away.

Nomenclature: First MPJ - the big toe joint Metatarsus primus elevatus - a functional or structural position of the first metatarsal First metatarsal - the foot bone making up the proximal portion of the big toe joint Hallux - the great toe

In addition, researchers have found that certain types of alcohol have less risk of causing gout than others. Of all the alcohols studied, it appears that Beer poses the highest risk of gout, while moderate consumption of wine or spirits has little to no increased risk of gout.

Other conditions - synovitis, crystal deposition diseases such as gout, systemic arthritis, external physical influences such as Dupytren's contracture, etc.

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